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A novel murine model of autoimmune dysautonomia by α3 nicotinic acetylcholine receptor immunization

We aimed to establish a novel murine model of autoimmune autonomic ganglionopathy (AAG), which represents autoimmune dysautonomia, associated with MHC class II to understand its pathomechanism and the pathogenicity of nicotinic acetylcholine receptor (nAChR) antibodies. The amino acid sequence of th...

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Detalles Bibliográficos
Autores principales: Yamakawa, Makoto, Nakane, Shunya, Ihara, Eikichi, Tawara, Nozomu, Ikeda, Hiroko, Igarashi, Yoko, Komohara, Yoshihiro, Takamatsu, Koutaro, Ikeda, Tokunori, Tomita, Yusuke, Murai, Shoichi, Ando, Yukio, Mukaino, Akihiro, Ogawa, Yoshihiro, Ueda, Mitsuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727251/
https://www.ncbi.nlm.nih.gov/pubmed/36507326
http://dx.doi.org/10.3389/fnins.2022.1006923