Cargando…

A novel murine model of autoimmune dysautonomia by α3 nicotinic acetylcholine receptor immunization

We aimed to establish a novel murine model of autoimmune autonomic ganglionopathy (AAG), which represents autoimmune dysautonomia, associated with MHC class II to understand its pathomechanism and the pathogenicity of nicotinic acetylcholine receptor (nAChR) antibodies. The amino acid sequence of th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamakawa, Makoto, Nakane, Shunya, Ihara, Eikichi, Tawara, Nozomu, Ikeda, Hiroko, Igarashi, Yoko, Komohara, Yoshihiro, Takamatsu, Koutaro, Ikeda, Tokunori, Tomita, Yusuke, Murai, Shoichi, Ando, Yukio, Mukaino, Akihiro, Ogawa, Yoshihiro, Ueda, Mitsuharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727251/ https://www.ncbi.nlm.nih.gov/pubmed/36507326 http://dx.doi.org/10.3389/fnins.2022.1006923

Ejemplares similares

gAChR antibodies in children and adolescents with acquired autoimmune dysautonomia in Japan
por: Yamakawa, Makoto, et al.
Publicado: (2021)

CSF TACI and BAFF levels in patients with primary CNS lymphoma as novel diagnostic biomarkers
por: Mizutani, Hironori, et al.
Publicado: (2018)

Involvement of Macrophages in the Pathogenesis of Familial Amyloid Polyneuropathy and Efficacy of Human iPS Cell-Derived Macrophages in Its Treatment
por: Suenaga, Genki, et al.
Publicado: (2016)

Immune checkpoint inhibitors in the onset of myasthenia gravis with hyperCKemia
por: Takamatsu, Koutaro, et al.
Publicado: (2018)

Ganglionic Acetylcholine Receptor Antibodies and Autonomic Dysfunction in Autoimmune Rheumatic Diseases
por: Imamura, Michie, et al.
Publicado: (2020)

Gut microbiota of Parkinson’s disease in an appendectomy cohort: a preliminary study
por: Nakahara, Keiichi, et al.
Publicado: (2023)

Binasal hemianopia caused by bilateral optic perineuritis due to sarcoidosis
por: Tawara, Nozomu, et al.
Publicado: (2021)

Autoimmune postural orthostatic tachycardia syndrome
por: Watari, Mari, et al.
Publicado: (2018)

Aging-associated and CD4 T-cell–dependent ectopic CXCL13 activation predisposes to anti–PD-1 therapy-induced adverse events
por: Tsukamoto, Hirotake, et al.
Publicado: (2022)

Anti-Kir4.1 Antibodies in Multiple Sclerosis: Specificity and Pathogenicity
por: Imamura, Michie, et al.
Publicado: (2020)

Cytometric cell-based assays for anti-striational antibodies in myasthenia gravis with myositis and/or myocarditis
por: Kufukihara, Kenji, et al.
Publicado: (2019)

Cancer therapy with major histocompatibility complex‐deficient and interferon β‐producing myeloid cells derived from allogeneic embryonic stem cells
por: Umemoto, Satoshi, et al.
Publicado: (2019)

Suppression of Th1-Mediated Autoimmunity by Embryonic Stem Cell-Derived Dendritic Cells
por: Ikeda, Tokunori, et al.
Publicado: (2014)

Inflammatory state exists in familial amyloid polyneuropathy that may be triggered by mutated transthyretin
por: Suenaga, Genki, et al.
Publicado: (2017)

Association between Anti-Ganglionic Nicotinic Acetylcholine Receptor (gAChR) Antibodies and HLA-DRB1 Alleles in the Japanese Population
por: Maeda, Yasuhiro, et al.
Publicado: (2016)

Statistical Concern Regarding the Relationship of Change in Mucus Plug Score with Airflow Over Time
por: Ikeda, Tokunori, et al.
Publicado: (2022)

Effectiveness of treatment for 31 patients with seropositive autoimmune autonomic ganglionopathy in Japan
por: Hayashi, Toshiyuki, et al.
Publicado: (2022)

Corosolic acid enhances the antitumor effects of chemotherapy on epithelial ovarian cancer by inhibiting signal transducer and activator of transcription 3 signaling
por: FUJIWARA, YUKIO, et al.
Publicado: (2013)

Clinical Features of Autoimmune Autonomic Ganglionopathy and the Detection of Subunit-Specific Autoantibodies to the Ganglionic Acetylcholine Receptor in Japanese Patients
por: Nakane, Shunya, et al.
Publicado: (2015)

Therapeutic Effect of Human iPS-Cell–Derived Myeloid Cells Expressing IFN-β against Peritoneally Disseminated Cancer in Xenograft Models
por: Koba, Chihiro, et al.
Publicado: (2013)

Application of iPS cell-derived macrophages to cancer therapy
por: Senju, Satoru, et al.
Publicado: (2014)

Association between neurosarcoidosis with autonomic dysfunction and anti-ganglionic acetylcholine receptor antibodies
por: Oishi, Makoto, et al.
Publicado: (2021)

The Risks and Benefits of Immune Checkpoint Blockade in Anti-AChR Antibody-Seropositive Non-Small Cell Lung Cancer Patients
por: Saruwatari, Koichi, et al.
Publicado: (2019)

Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment
por: Pan, Cheng, et al.
Publicado: (2020)

Dysautonomia in Alzheimer's Disease
por: Tulbă, Delia, et al.
Publicado: (2020)

COVID-19 Dysautonomia
por: Goodman, Brent P., et al.
Publicado: (2021)

Onigiri Esophagography as a Screening Test for Esophageal Motility Disorders
por: Hamada, Shohei, et al.
Publicado: (2022)

Cytoplasmic p53 aggregates accumulated in p53-mutated cancer correlate with poor prognosis
por: Iwahashi, Naoyuki, et al.
Publicado: (2022)

A Novel Strategy for Inducing the Antitumor Effects of Triterpenoid Compounds: Blocking the Protumoral Functions of Tumor-Associated Macrophages via STAT3 Inhibition
por: Fujiwara, Yukio, et al.
Publicado: (2014)

Cholesterol metabolism and lipid droplet vacuoles; a potential target for the therapy of aggressive lymphoma
por: Yano, Hiromu, et al.
Publicado: (2022)

BCG vaccine may generate cross-reactive T cells against SARS-CoV-2: In silico analyses and a hypothesis
por: Tomita, Yusuke, et al.
Publicado: (2020)

Association between HLA gene polymorphisms and mortality of COVID‐19: An in silico analysis
por: Tomita, Yusuke, et al.
Publicado: (2020)

Fingolimod-induced decrease in heart rate may predict subsequent decreasing degree of lymphocytes
por: Ikeda, Tokunori, et al.
Publicado: (2018)

Author Correction: Fingolimod-induced decrease in heart rate may predict subsequent decreasing degree of lymphocytes
por: Ikeda, Tokunori, et al.
Publicado: (2019)

Onionin A inhibits small-cell lung cancer proliferation through suppressing STAT3 activation induced by macrophages-derived IL-6 and cell–cell interaction with tumor-associated macrophage
por: Mito, Remi, et al.
Publicado: (2023)

Dysautonomia, fibromyalgia and reflex dystrophy
por: Eisinger, Jean
Publicado: (2007)

Familial Dysautonomia: Mechanisms and Models
por: Dietrich, Paula, et al.
Publicado: (2016)

Dysautonomia: an Explanation for the Medically Unexplained?
por: Chandrasekaram, Senthil, et al.
Publicado: (2016)

COVID-19-Associated Dysautonomia
por: Suresh, Krithika, et al.
Publicado: (2021)

Dysautonomia in two littermate kittens
por: Černá, Petra, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c42mt5atbv4n946399276quu3l