The differential in vivo contribution of spinal α(2A)- and α(2C)-adrenoceptors in tonic and acute evoked nociception in the rat

Spinal α(2)-adrenoceptor induces analgesia by neuronal inhibition of primary afferent fibers. This family receptor coupled to G( i/o ) proteins can be subdivided into three functional subtypes: α(2A), α(2B,) and α(2C)-adrenoceptors, and current evidence on spinal analgesia supports the relevance of...

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Detalles Bibliográficos
Autores principales: López-Córdoba, Gustavo, Martínez-Lorenzana, Guadalupe, Lozano-Cuenca, Jair, Condés-Lara, Miguel, González-Hernández, Abimael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727263/
https://www.ncbi.nlm.nih.gov/pubmed/36506544
http://dx.doi.org/10.3389/fphar.2022.1023611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727263/
https://www.ncbi.nlm.nih.gov/pubmed/36506544
http://dx.doi.org/10.3389/fphar.2022.1023611

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