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Targeted alpha therapy with the (224)Ra/(212)Pb-TCMC-TP-3 dual alpha solution in a multicellular tumor spheroid model of osteosarcoma

Osteosarcoma patients with overt metastases at primary diagnosis have a 5-year survival rate of less than 20%. TP-3 is a murine IgG2b monoclonal antibody with high affinity for an epitope residing on the p80 osteosarcoma cell surface membrane antigen. The tumor-associated antigen p80 is overexpresse...

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Detalles Bibliográficos
Autores principales:	Tornes, Anna Julie Kjøl, Stenberg, Vilde Yuli, Larsen, Roy Hartvig, Bruland, Øyvind Sverre, Revheim, Mona-Elisabeth, Juzeniene, Asta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727293/ https://www.ncbi.nlm.nih.gov/pubmed/36507500 http://dx.doi.org/10.3389/fmed.2022.1058863

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