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SIRT1, a novel transcriptional downstream target of CD44, linking its deacetylase activity to tumor cell invasion/metastasis

Our tetracycline-off-inducible CD44 expression system previously established in mouse model, revealed that activation of CD44 with its major ligand hyaluronan (HA) promoted breast cancer (BC) metastasis to the liver. To identify the mechanisms that underpin CD44-promoted BC cell invasion, microarray...

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Detalles Bibliográficos
Autores principales:	Ahmad, Salma M. S., Al-Mansoob, Maryam, Ouhtit, Allal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727296/ https://www.ncbi.nlm.nih.gov/pubmed/36505828 http://dx.doi.org/10.3389/fonc.2022.1038121

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