Comparison of High-Resolution Melting (HRM) Analysis with Direct Sequencing for the Detection of DNMT3A Mutations in AML Patients

OBJECTIVE: Acute myeloid leukemia (AML) is caused by abnormal gene expression following mutations. Many of the mutations in AML lead to gene instability and poor response to treatment. Among these mutations, DNMT3A mutation is exceedingly important due to its major role in methylation and its effect...

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Detalles Bibliográficos
Autores principales: Moonesi, Mohammadreza, Zaka Khosravi, Saeed, Moradabadi, Alireza, Rajaeinejad, Mohsen, Heidari, Mohammad Foad, Mahjub, Golnoosh, Noroozi-Aghideh, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727341/
https://www.ncbi.nlm.nih.gov/pubmed/35901322
http://dx.doi.org/10.31557/APJCP.2022.23.7.2185

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