Cargando…

A Double-Blind, Placebo-Controlled Randomized Phase IIa Study: Evaluating the Effect of Curcumin for Treatment of Cancer Anorexia–Cachexia Syndrome in Solid Cancer Patients

OBJECTIVE: We aim to investigate the effect of curcumin on preventing cancer anorexia–cachexia syndrome (CACS) via through mechanism of inhibition on NF-kB signal pathway. Outcome measurement for primary end point was improvement of body tissue composition, and the secondary end points were body wei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chaiworramukkul, Aornchuma, Seetalarom, Kasan, Saichaemchan, Siriwimon, Prasongsook, Naiyarat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727370/ https://www.ncbi.nlm.nih.gov/pubmed/35901339 http://dx.doi.org/10.31557/APJCP.2022.23.7.2333

Ejemplares similares

Efficacy of Curcumin on Treating Cancer Anorexia-Cachexia Syndrome in Locally or Advanced Head and Neck Cancer: A Double-Blind, Placebo-Controlled Randomised Phase IIa Trial (CurChexia)
por: Thambamroong, Tawasapon, et al.
Publicado: (2022)

A Pilot Study of Using Smartphone Application vs. Routine Follow-Up for Patient Care in Advanced Non-Small Cell Lung Cancer During the COVID-19 Pandemic Era
por: Prasongsook, Naiyarat, et al.
Publicado: (2022)

Impact of interprofessional collaborative practice in palliative care on outcomes for advanced cancer inpatients in a resource-limited setting
por: Pornrattanakavee, Pitchayapa, et al.
Publicado: (2022)

The Effect of Intravenous Mannitol Combined With Normal Saline in Preventing Cisplatin-Induced Nephrotoxicity: A Randomized, Double-Blind, Placebo-Controlled Trial
por: Sainamthip, Panot, et al.
Publicado: (2022)

Single dose dexamethasone prophylaxis of postembolisation syndrome after chemoembolisation in hepatocellular carcinoma patient: A randomised, double-blind, placebo-controlled study
por: Sainamthip, Panot, et al.
Publicado: (2021)

Understanding and Targeting MET Signaling in Solid Tumors - Are We There Yet?
por: Ariyawutyakorn, Witthawat, et al.
Publicado: (2016)

Cachexia-anorexia in cancer patients
Publicado: (1996)

Safety, tolerability and pharmacokinetics of intravenous ghrelin for cancer-related anorexia/cachexia: a randomised, placebo-controlled, double-blind, double-crossover study
por: Strasser, F, et al.
Publicado: (2008)

Pathophysiology of anorexia in the cancer cachexia syndrome
por: Ezeoke, Chukwuemeka Charles, et al.
Publicado: (2015)

Effects of Animal Venoms and Toxins on Hallmarks of Cancer
por: Chaisakul, Janeyuth, et al.
Publicado: (2016)

Optimal management of cancer anorexia–cachexia syndrome
por: Argilés, Josep M, et al.
Publicado: (2010)

A double blind placebo controlled trial of medroxyprogesterone acetate (MPA) in cancer cachexia.
por: Downer, S., et al.
Publicado: (1993)

Megestrol acetate in cachexia and anorexia
por: Yeh, Shing-shing, et al.
Publicado: (2006)

Leptin in Anorexia and Cachexia Syndrome
por: Engineer, Diana R., et al.
Publicado: (2012)

Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia
por: Peixoto da Silva, Sara, et al.
Publicado: (2020)

Understanding the molecular basis of anorexia and tissue wasting in cancer cachexia
por: Yeom, Eunbyul, et al.
Publicado: (2022)

Pentoxifylline treatment in patients with cancer cachexia: A double-blind, randomized, placebo-controlled clinical trial
por: Mehrzad, Valiollah, et al.
Publicado: (2016)

Potentiation of ghrelin signaling attenuates cancer anorexia–cachexia and prolongs survival
por: Fujitsuka, N, et al.
Publicado: (2011)

Drugs in development for treatment of patients with cancer-related anorexia and cachexia syndrome
por: Mantovani, Giovanni, et al.
Publicado: (2013)

Proteomic profiling of the hypothalamus in a mouse model of cancer-induced anorexia-cachexia
por: Ihnatko, R, et al.
Publicado: (2013)

Evidence for partial pharmaceutical reversal of the cancer anorexia–cachexia syndrome: the case of anamorelin
por: Anker, Stefan D, et al.
Publicado: (2015)

Drugs in development for treatment of patients with cancer-related anorexia and cachexia syndrome [Retraction]
Publicado: (2013)

Mirtazapine versus Megestrol in the Treatment of Anorexia–Cachexia Syndrome in Patients with Advanced Cancer: A Randomized, Double-Blind, Controlled Phase II Clinical Trial
por: Almeida, Olga Laura Sena, et al.
Publicado: (2023)

Prospective, randomized, double-blind, placebo-controlled phase IIa clinical trial on the effects of an estrogen-progestin combination as add-on to inpatient psychotherapy in adult female patients suffering from anorexia nervosa
por: Paslakis, Georgios, et al.
Publicado: (2018)

Efficacy and Safety of Sipjeondaebo-Tang for Anorexia in Patients with Cancer: A Pilot, Randomized, Double-Blind, Placebo-Controlled Trial
por: Cheon, Chunhoo, et al.
Publicado: (2017)

Effect of rosuvastatin on diabetic polyneuropathy: a randomized, double-blind, placebo-controlled Phase IIa study
por: Hernández-Ojeda, Jaime, et al.
Publicado: (2014)

Glycoproteomic Analysis Reveals Aberrant Expression of Complement C9 and Fibronectin in the Plasma of Patients with Colorectal Cancer
por: Chantaraamporn, Juthamard, et al.
Publicado: (2020)

Corrigendum to “Efficacy and Safety of Sipjeondaebo-Tang for Anorexia in Patients with Cancer: A Pilot, Randomized, Double-Blind, Placebo-Controlled Trial”
por: Cheon, Chunhoo, et al.
Publicado: (2018)

A randomised, double blind, placebo-controlled trial of megestrol acetate or dexamethasone in treating symptomatic anorexia in people with advanced cancer
por: Currow, David C., et al.
Publicado: (2021)

Rikkunshito, a ghrelin potentiator, ameliorates anorexia–cachexia syndrome
por: Fujitsuka, Naoki, et al.
Publicado: (2014)

Megestrol acetate for cachexia–anorexia syndrome. A systematic review
por: Ruiz‐García, Vicente, et al.
Publicado: (2018)

Plasma Ghrelin Levels Are Associated with Anorexia but Not Cachexia in Patients with NSCLC
por: Blauwhoff-Buskermolen, Susanne, et al.
Publicado: (2017)

Cachexia Anorexia Syndrome and Associated Metabolic Dysfunction in Peritoneal Metastasis
por: Archid, Rami, et al.
Publicado: (2019)

A randomized, double-blind, placebo-controlled phase IIa trial of efruxifermin for patients with compensated NASH cirrhosis
por: Harrison, Stephen A., et al.
Publicado: (2022)

Effect of Sipjeondaebo-Tang on Cancer-Induced Anorexia and Cachexia in CT-26 Tumor-Bearing Mice
por: Choi, Youn Kyung, et al.
Publicado: (2014)

Safety of Megestrol Acetate in Palliating Anorexia-Cachexia Syndrome in Patients with Castration-Resistant Prostate Cancer
por: Hong, Sungwoo, et al.
Publicado: (2013)

Anamorelin hydrochloride in the treatment of cancer anorexia–cachexia syndrome: design, development, and potential place in therapy
por: Graf, Solomon A, et al.
Publicado: (2017)

Anorexia of ageing: a key component in the pathogenesis of both sarcopenia and cachexia
por: Morley, John E.
Publicado: (2017)

Double-blind randomized placebo-controlled multicenter clinical trial (phase IIa) on diindolylmethane’s efficacy and safety in the treatment of CIN: implications for cervical cancer prevention
por: Ashrafian, Levon, et al.
Publicado: (2015)

A Systematic Review and Meta-Analysis of the Clinical Use of Megestrol Acetate for Cancer-Related Anorexia/Cachexia
por: Lim, Yu Liang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_07lmiglhcatk7n98m1kn8dvffl