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Integrated transcriptomic and metabolomic profiling reveals dysregulation of purine metabolism during the acute phase of spinal cord injury in rats

INTRODUCTION: Spinal cord injury (SCI) results in drastic dysregulation of microenvironmental metabolism during the acute phase, which greatly affects neural recovery. A better insight into the potential molecular pathways of metabolic dysregulation by multi-omics analysis could help to reveal targe...

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Detalles Bibliográficos
Autores principales: Zeng, Zhong, Li, Mei, Jiang, Zhanfeng, Lan, Yuanxiang, Chen, Lei, Chen, Yanjun, Li, Hailiang, Hui, Jianwen, Zhang, Lijian, Hu, Xvlei, Xia, Hechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727392/
https://www.ncbi.nlm.nih.gov/pubmed/36507345
http://dx.doi.org/10.3389/fnins.2022.1066528