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Mechanism of action of paclitaxel for treating glioblastoma based on single-cell RNA sequencing data and network pharmacology

Paclitaxel is an herbal active ingredient used in clinical practice that shows anti-tumor effects. However, its biological activity, mechanism, and cancer cell-killing effects remain unknown. Information on the chemical gene interactions of paclitaxel was obtained from the Comparative Toxicogenomics...

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Detalles Bibliográficos
Autores principales:	Lu, Jianglong, Xu, Fanjie, Rao, Changjun, Shen, Chaodong, Jin, Jinghao, Zhu, Zhangzhang, Wang, Chengde, Li, Qun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727555/ https://www.ncbi.nlm.nih.gov/pubmed/36506527 http://dx.doi.org/10.3389/fphar.2022.1076958

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