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Membrane fusion by Drosophila atlastin does not require GTP hydrolysis

Atlastin (ATL) GTPases undergo trans dimerization and a power strokelike crossover conformational rearrangement to drive endoplasmic reticulum membrane fusion. Fusion depends on GTP, but the role of nucleotide hydrolysis has remained controversial. For instance, nonhydrolyzable GTP analogs block fus...

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Detalles Bibliográficos
Autores principales: Crosby, Daniel, Lee, Tina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727788/
https://www.ncbi.nlm.nih.gov/pubmed/36129776
http://dx.doi.org/10.1091/mbc.E22-05-0164

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