Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis

The coatomer protein complex 1 (COPI) is a multisubunit complex that coats intracellular vesicles and is involved in intracellular protein trafficking. Recently we and others found that depletion of COPI complex subunits zeta (COPZ1) and delta (ARCN1) preferentially kills tumor cells relative to nor...

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Detalles Bibliográficos
Autores principales: Gasparian, A., Aksenova, M., Oliver, D., Levina, E., Doran, R., Lucius, M., Piroli, G., Oleinik, N., Ogretmen, B., Mythreye, K., Frizzell, N., Broude, E., Wyatt, M. D., Shtutman, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727790/
https://www.ncbi.nlm.nih.gov/pubmed/36222847
http://dx.doi.org/10.1091/mbc.E21-08-0420

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