p115RhoGEF activates RhoA to support tight junction maintenance and remodeling

In vertebrates, epithelial cell–cell junctions must rapidly remodel to maintain barrier function as cells undergo dynamic shape-change events. Consequently, localized leaks sometimes arise within the tight junction (TJ) barrier, which are repaired by short-lived activations of RhoA, called “Rho flar...

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Detalles Bibliográficos
Autores principales: Chumki, Shahana A., van den Goor, Lotte M., Hall, Benjamin N., Miller, Ann L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727809/
https://www.ncbi.nlm.nih.gov/pubmed/36200892
http://dx.doi.org/10.1091/mbc.E22-06-0205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727809/
https://www.ncbi.nlm.nih.gov/pubmed/36200892
http://dx.doi.org/10.1091/mbc.E22-06-0205

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