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p115RhoGEF activates RhoA to support tight junction maintenance and remodeling
In vertebrates, epithelial cell–cell junctions must rapidly remodel to maintain barrier function as cells undergo dynamic shape-change events. Consequently, localized leaks sometimes arise within the tight junction (TJ) barrier, which are repaired by short-lived activations of RhoA, called “Rho flar...
Autores principales: | Chumki, Shahana A., van den Goor, Lotte M., Hall, Benjamin N., Miller, Ann L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727809/ https://www.ncbi.nlm.nih.gov/pubmed/36200892 http://dx.doi.org/10.1091/mbc.E22-06-0205 |
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