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Emerin prevents BAF-mediated aggregation of lamin A on chromosomes in telophase to allow nuclear membrane expansion and nuclear lamina formation

Several studies have suggested a role for the LEM-domain protein emerin and the DNA binding factor BAF in nuclear envelope reformation after mitosis, but the exact molecular mechanisms are not understood. Using HeLa cells deficient for emerin or both emerin and lamin A, we show that emerin deficienc...

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Detalles Bibliográficos
Autores principales: Snyers, L., Löhnert, R., Weipoltshammer, K., Schöfer, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727812/
https://www.ncbi.nlm.nih.gov/pubmed/36200863
http://dx.doi.org/10.1091/mbc.E22-01-0007