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Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei

Chromosome segregation requires assembly of the macromolecular kinetochore complex onto centromeric DNA. While most eukaryotes have canonical kinetochore proteins that are widely conserved among eukaryotes, evolutionarily divergent kinetoplastids have a unique set of kinetochore proteins. Little is...

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Detalles Bibliográficos
Autores principales: Ishii, Midori, Ludzia, Patryk, Marcianò, Gabriele, Allen, William, Nerusheva, Olga O., Akiyoshi, Bungo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727816/
https://www.ncbi.nlm.nih.gov/pubmed/36129769
http://dx.doi.org/10.1091/mbc.E22-07-0269-T