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Factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department
BACKGROUND: Unfavorable outcomes occur in patients with acute abdominal pain who visit the emergency department (ED). We aimed to determine the factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the ED. METHODS: This retrospective cohort study was conducted f...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727909/ https://www.ncbi.nlm.nih.gov/pubmed/36474160 http://dx.doi.org/10.1186/s12873-022-00761-y |
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author | Dadeh, Ar-aishah |
author_facet | Dadeh, Ar-aishah |
author_sort | Dadeh, Ar-aishah |
collection | PubMed |
description | BACKGROUND: Unfavorable outcomes occur in patients with acute abdominal pain who visit the emergency department (ED). We aimed to determine the factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the ED. METHODS: This retrospective cohort study was conducted from July 1, 2015 to June 30, 2016. The inclusion criterion was patients aged older than 18 years who presented to the ED with acute abdominal pain. Significant factors associated with unfavorable outcomes were examined using univariate and multivariate logistic regression analyses. RESULTS: A total of 951 patients were included in the study. Multivariate logistic regression analysis showed that the ED length of stay (EDLOS) > 4 h (adjusted odds ratio (AOR) 2.62, 95% confidence interval [CI]: 1.33–5.14; p = 0.005), diastolic blood pressure (DBP) < 80 mmHg (AOR 3.31, 95% CI: 1.71–6.4; p ≤ 0.001), respiratory rate ≥ 24 breaths/min (AOR 2.03, 95% CI: 1.07–3.86; p ≤ 0.031), right lower quadrant (RLQ) tenderness (AOR 3.72, 95% CI: 1.89–7.32; p ≤ 0.001), abdominal distension (AOR 2.91, 95% CI: 1.29–6.57; p = 0.010), hypoactive bowel sounds (AOR 2.89, 95% CI: 1.09–7.67; p = 0.033), presence of specific abdominal signs (AOR 2.07, 95% CI: 1.1–3.88; p = 0.024), white blood cell count ≥ 12,000 cells/mm(3) (AOR 2.37, 95% CI: 1.22–4.6; p = 0.011), and absolute neutrophil count (ANC) > 75% (AOR 2.83, 95% CI: 1.39–5.75; p = 0.004) were revealed as significant factors associated with unfavorable outcomes. CONCLUSIONS: The present study revealed that the significant clinical signs associated with the occurrence of unfavorable outcomes were DBP < 80 mmHg, tachypnea (≥ 24 breaths/min), RLQ tenderness, abdominal distension, hypoactive bowel sounds, and presence of specific abdominal signs. Moreover, the associated laboratory results identified in this study were leukocytosis and ANC > 75%. Additionally, patients with abdominal pain visiting the ED who had an EDLOS longer than 4 h were associated with unfavorable outcomes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12873-022-00761-y. |
format | Online Article Text |
id | pubmed-9727909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-97279092022-12-08 Factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department Dadeh, Ar-aishah BMC Emerg Med Research BACKGROUND: Unfavorable outcomes occur in patients with acute abdominal pain who visit the emergency department (ED). We aimed to determine the factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the ED. METHODS: This retrospective cohort study was conducted from July 1, 2015 to June 30, 2016. The inclusion criterion was patients aged older than 18 years who presented to the ED with acute abdominal pain. Significant factors associated with unfavorable outcomes were examined using univariate and multivariate logistic regression analyses. RESULTS: A total of 951 patients were included in the study. Multivariate logistic regression analysis showed that the ED length of stay (EDLOS) > 4 h (adjusted odds ratio (AOR) 2.62, 95% confidence interval [CI]: 1.33–5.14; p = 0.005), diastolic blood pressure (DBP) < 80 mmHg (AOR 3.31, 95% CI: 1.71–6.4; p ≤ 0.001), respiratory rate ≥ 24 breaths/min (AOR 2.03, 95% CI: 1.07–3.86; p ≤ 0.031), right lower quadrant (RLQ) tenderness (AOR 3.72, 95% CI: 1.89–7.32; p ≤ 0.001), abdominal distension (AOR 2.91, 95% CI: 1.29–6.57; p = 0.010), hypoactive bowel sounds (AOR 2.89, 95% CI: 1.09–7.67; p = 0.033), presence of specific abdominal signs (AOR 2.07, 95% CI: 1.1–3.88; p = 0.024), white blood cell count ≥ 12,000 cells/mm(3) (AOR 2.37, 95% CI: 1.22–4.6; p = 0.011), and absolute neutrophil count (ANC) > 75% (AOR 2.83, 95% CI: 1.39–5.75; p = 0.004) were revealed as significant factors associated with unfavorable outcomes. CONCLUSIONS: The present study revealed that the significant clinical signs associated with the occurrence of unfavorable outcomes were DBP < 80 mmHg, tachypnea (≥ 24 breaths/min), RLQ tenderness, abdominal distension, hypoactive bowel sounds, and presence of specific abdominal signs. Moreover, the associated laboratory results identified in this study were leukocytosis and ANC > 75%. Additionally, patients with abdominal pain visiting the ED who had an EDLOS longer than 4 h were associated with unfavorable outcomes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12873-022-00761-y. BioMed Central 2022-12-06 /pmc/articles/PMC9727909/ /pubmed/36474160 http://dx.doi.org/10.1186/s12873-022-00761-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Dadeh, Ar-aishah Factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department |
title | Factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department |
title_full | Factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department |
title_fullStr | Factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department |
title_full_unstemmed | Factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department |
title_short | Factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department |
title_sort | factors associated with unfavorable outcomes in patients with acute abdominal pain visiting the emergency department |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727909/ https://www.ncbi.nlm.nih.gov/pubmed/36474160 http://dx.doi.org/10.1186/s12873-022-00761-y |
work_keys_str_mv | AT dadeharaishah factorsassociatedwithunfavorableoutcomesinpatientswithacuteabdominalpainvisitingtheemergencydepartment |