Intestinal Apc‐inactivation induces HSP25 dependency

The majority of colorectal cancers (CRCs) present with early mutations in tumor suppressor gene APC. APC mutations result in oncogenic activation of the Wnt pathway, which is associated with hyperproliferation, cytoskeletal remodeling, and a global increase in mRNA translation. To compensate for the...

Descripción completa

Detalles Bibliográficos
Autores principales: van Neerven, Sanne M, Smit, Wouter L, van Driel, Milou S, Kakkar, Vaishali, de Groot, Nina E, Nijman, Lisanne E, Elbers, Clara C, Léveillé, Nicolas, Heijmans, Jarom, Vermeulen, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727927/
https://www.ncbi.nlm.nih.gov/pubmed/36321561
http://dx.doi.org/10.15252/emmm.202216194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727927/
https://www.ncbi.nlm.nih.gov/pubmed/36321561
http://dx.doi.org/10.15252/emmm.202216194

Ejemplares similares