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Expression of CFTR, a hallmark gene of ionocytes, is downregulated in salivary glands of Sjögren’s syndrome patients

INTRODUCTION: The autoimmune exocrinopathy, Sjögren’s syndrome (SjS), is associated with secretory defects in salivary glands. The cystic fibrosis transmembrane conductance regulator (CFTR) of the chloride channel is a master regulator of fluid secretion, but its role in SjS has not been investigate...

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Detalles Bibliográficos
Autores principales:	Zhang, Qi, Lv, Xiuying, Wang, Ying, Wang, Bin, He, Yan, Chen, Chubing, Shi, Guixiu, Li, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727938/ https://www.ncbi.nlm.nih.gov/pubmed/36476557 http://dx.doi.org/10.1186/s13075-022-02959-8

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