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IQCN disruption causes fertilization failure and male infertility due to manchette assembly defect

Total fertilization failure (TFF) is an important cause of infertility; however, the genetic basis of TFF caused by male factors remains to be clarified. In this study, whole‐exome sequencing was firstly used to screen for genetic causes of TFF after intracytoplasmic sperm injection (ICSI), and homo...

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Detalles Bibliográficos
Autores principales: Dai, Jing, Li, Qi, Zhou, Qinwei, Zhang, Shen, Chen, Junru, Wang, Yize, Guo, Jing, Gu, Yifan, Gong, Fei, Tan, Yueqiu, Lu, Guangxiu, Zheng, Wei, Lin, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728048/
https://www.ncbi.nlm.nih.gov/pubmed/36321563
http://dx.doi.org/10.15252/emmm.202216501