Disrupting metformin adaptation of liver cancer cells by targeting the TOMM34/ATP5B axis

Metformin, a well‐known antidiabetic drug, has been repurposed for cancer treatment; however, recently observed drug resistance and tumor metastasis have questioned its further application. Here, we found that long‐term metformin exposure led to metabolic adaptation of hepatocellular carcinoma (HCC)...

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Detalles Bibliográficos
Autores principales: Jin, Ping, Jiang, Jingwen, Zhou, Li, Huang, Zhao, Qin, Siyuan, Chen, Hai‐Ning, Peng, Liyuan, Zhang, Zhe, Li, Bowen, Luo, Maochao, Zhang, Tingting, Ming, Hui, Ding, Ning, Li, Lei, Xie, Na, Gao, Wei, Zhang, Wei, Nice, Edouard C, Wei, Yuquan, Huang, Canhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728056/
https://www.ncbi.nlm.nih.gov/pubmed/36321555
http://dx.doi.org/10.15252/emmm.202216082

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