Sex differences and risk factors for bleeding in Alagille syndrome

Spontaneous bleeds are a leading cause of death in the pediatric JAG1‐related liver disease Alagille syndrome (ALGS). We asked whether there are sex differences in bleeding events in patients, whether Jag1 ( Ndr/Ndr ) mice display bleeds or vascular defects, and whether discovered vascular pathology...

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Detalles Bibliográficos
Autores principales: Hankeova, Simona, Van Hul, Noemi, Laznovsky, Jakub, Verboven, Elisabeth, Mangold, Katrin, Hensens, Naomi, Adori, Csaba, Verhoef, Elvira, Zikmund, Tomas, Dawit, Feven, Kavkova, Michaela, Salplachta, Jakub, Sjöqvist, Marika, Johansson, Bengt R, Hassan, Mohamed G, Fredriksson, Linda, Baumgärtel, Karsten, Bryja, Vitezslav, Lendahl, Urban, Jheon, Andrew, Alten, Florian, Fahnehjelm, Kristina Teär, Fischler, Björn, Kaiser, Jozef, Andersson, Emma R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728057/
https://www.ncbi.nlm.nih.gov/pubmed/36345711
http://dx.doi.org/10.15252/emmm.202215809

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