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Epidemiology of invasive Haemophilus influenzae serotype a disease in the North American Arctic, 2006–2017
Invasive Haemophilus influenzae type a (iHia) disease was detected in Alaska and Northern Canada in 2002 and 2000, respectively. From 2006 to 2017, 164 iHia cases (Alaska=53, Northern Canada=111) were reported. Rates of iHia disease per 100,000 persons were higher in Northern Canada compared to Alas...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728126/ https://www.ncbi.nlm.nih.gov/pubmed/36461156 http://dx.doi.org/10.1080/22423982.2022.2150382 |
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author | Zulz, Tammy Huang, Grace Rudolph, Karen DeByle, Carolynn Tsang, Raymond Desai, Shalini Massey, Stephanie Bruce, Michael G |
author_facet | Zulz, Tammy Huang, Grace Rudolph, Karen DeByle, Carolynn Tsang, Raymond Desai, Shalini Massey, Stephanie Bruce, Michael G |
author_sort | Zulz, Tammy |
collection | PubMed |
description | Invasive Haemophilus influenzae type a (iHia) disease was detected in Alaska and Northern Canada in 2002 and 2000, respectively. From 2006 to 2017, 164 iHia cases (Alaska=53, Northern Canada=111) were reported. Rates of iHia disease per 100,000 persons were higher in Northern Canada compared to Alaska and were significantly higher in Indigenous (Alaska 2.8, Northern Canada 9.5) compared to non-Indigenous populations (Alaska 0.1, Northern Canada=0.4). Disease rates were highest in Indigenous children <2 years of age (Alaska 56.2, Northern Canada=144.1) and significantly higher than in non-Indigenous children <2 (Alaska 0.1, Northern Canada 0.4). The most common clinical presentation in children <5 years was meningitis of age and pneumonia in persons ≥5 years old. Most patients were hospitalised (Alaska=87%, Northern Canada=89%) and fatality was similar (Alaska=11%, Northern Canada=10%). MLST testing showed sequence types ST23 and ST576 in Northern Canada and ST576, ST23 and ST56 in Alaska. Alaska and Northern Canada have high rates of iHia disease. A vaccine is needed in these regions to protect young children. |
format | Online Article Text |
id | pubmed-9728126 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-97281262022-12-08 Epidemiology of invasive Haemophilus influenzae serotype a disease in the North American Arctic, 2006–2017 Zulz, Tammy Huang, Grace Rudolph, Karen DeByle, Carolynn Tsang, Raymond Desai, Shalini Massey, Stephanie Bruce, Michael G Int J Circumpolar Health Original Research Article Invasive Haemophilus influenzae type a (iHia) disease was detected in Alaska and Northern Canada in 2002 and 2000, respectively. From 2006 to 2017, 164 iHia cases (Alaska=53, Northern Canada=111) were reported. Rates of iHia disease per 100,000 persons were higher in Northern Canada compared to Alaska and were significantly higher in Indigenous (Alaska 2.8, Northern Canada 9.5) compared to non-Indigenous populations (Alaska 0.1, Northern Canada=0.4). Disease rates were highest in Indigenous children <2 years of age (Alaska 56.2, Northern Canada=144.1) and significantly higher than in non-Indigenous children <2 (Alaska 0.1, Northern Canada 0.4). The most common clinical presentation in children <5 years was meningitis of age and pneumonia in persons ≥5 years old. Most patients were hospitalised (Alaska=87%, Northern Canada=89%) and fatality was similar (Alaska=11%, Northern Canada=10%). MLST testing showed sequence types ST23 and ST576 in Northern Canada and ST576, ST23 and ST56 in Alaska. Alaska and Northern Canada have high rates of iHia disease. A vaccine is needed in these regions to protect young children. Taylor & Francis 2022-12-02 /pmc/articles/PMC9728126/ /pubmed/36461156 http://dx.doi.org/10.1080/22423982.2022.2150382 Text en This work was authored as part of the Contributor’s official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 USC. 105, no copyright protection is available for such works under US Law. https://creativecommons.org/publicdomain/mark/1.0/This is an Open Access article that has been identified as being free of known restrictions under copyright law, including all related and neighboring rights (https://creativecommons.org/publicdomain/mark/1.0/). You can copy, modify, distribute and perform the work, even for commercial purposes, all without asking permission. |
spellingShingle | Original Research Article Zulz, Tammy Huang, Grace Rudolph, Karen DeByle, Carolynn Tsang, Raymond Desai, Shalini Massey, Stephanie Bruce, Michael G Epidemiology of invasive Haemophilus influenzae serotype a disease in the North American Arctic, 2006–2017 |
title | Epidemiology of invasive Haemophilus influenzae serotype a disease in the North American Arctic, 2006–2017 |
title_full | Epidemiology of invasive Haemophilus influenzae serotype a disease in the North American Arctic, 2006–2017 |
title_fullStr | Epidemiology of invasive Haemophilus influenzae serotype a disease in the North American Arctic, 2006–2017 |
title_full_unstemmed | Epidemiology of invasive Haemophilus influenzae serotype a disease in the North American Arctic, 2006–2017 |
title_short | Epidemiology of invasive Haemophilus influenzae serotype a disease in the North American Arctic, 2006–2017 |
title_sort | epidemiology of invasive haemophilus influenzae serotype a disease in the north american arctic, 2006–2017 |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728126/ https://www.ncbi.nlm.nih.gov/pubmed/36461156 http://dx.doi.org/10.1080/22423982.2022.2150382 |
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