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Development of Non-Immunosuppressive FK506 Derivatives as Antifungal and Neurotrophic Agents
FK506, also known as tacrolimus, is a clinically important immunosuppressant drug and has promising therapeutic potentials owing to its antifungal, neuroprotective, and neuroregenerative activities. To generate various FK506 derivatives, the structure of FK506 has been modified by chemical methods o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Microbiology and Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728173/ https://www.ncbi.nlm.nih.gov/pubmed/31752059 http://dx.doi.org/10.4014/jmb.1911.11008 |