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Fulminans Purpura due to Morganella morganii

Purpura fulminans (PF) is a dermatological manifestation of a life-threatening condition characterized by disseminated intravascular coagulation and endovascular thrombosis. The idiopathic/infectious form is the most common and usually associated with infection by Neisseria meningitidis or Streptoco...

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Autores principales: Guerra, Mariana, Marado, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728211/
https://www.ncbi.nlm.nih.gov/pubmed/36506741
http://dx.doi.org/10.12890/2022_003670
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author Guerra, Mariana
Marado, Daniela
author_facet Guerra, Mariana
Marado, Daniela
author_sort Guerra, Mariana
collection PubMed
description Purpura fulminans (PF) is a dermatological manifestation of a life-threatening condition characterized by disseminated intravascular coagulation and endovascular thrombosis. The idiopathic/infectious form is the most common and usually associated with infection by Neisseria meningitidis or Streptococcus pneumoniae. We describe a case of Morganella morganii-induced bacteriaemia complicated with PF in an individual who had undergone a recent urinary tract infection intervention. The patient presented with purpuric skin lesions, fever and hypotension but had no alterations in coagulation parameters or disseminated intravascular coagulation. Aggressive early resuscitation, intravenous antibiotics and wound care were essential to a favourable response. LEARNING POINTS: Purpura fulminans is a dermatological manifestation of an underlying life-threatening condition, and is characterized by disseminated intravascular coagulation and skin necrosis. It is a morbid and potentially fatal condition that can be a cutaneous manifestation of Morganella morganii bacteraemia. Early identification and accurate diagnosis of the underlying cause can help minimize morbidity and mortality; management should be tailored to the individual, with the use of intravenous antibiotics, necrotic skin excision and aggressive early resuscitation.
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spelling pubmed-97282112022-12-08 Fulminans Purpura due to Morganella morganii Guerra, Mariana Marado, Daniela Eur J Case Rep Intern Med Articles Purpura fulminans (PF) is a dermatological manifestation of a life-threatening condition characterized by disseminated intravascular coagulation and endovascular thrombosis. The idiopathic/infectious form is the most common and usually associated with infection by Neisseria meningitidis or Streptococcus pneumoniae. We describe a case of Morganella morganii-induced bacteriaemia complicated with PF in an individual who had undergone a recent urinary tract infection intervention. The patient presented with purpuric skin lesions, fever and hypotension but had no alterations in coagulation parameters or disseminated intravascular coagulation. Aggressive early resuscitation, intravenous antibiotics and wound care were essential to a favourable response. LEARNING POINTS: Purpura fulminans is a dermatological manifestation of an underlying life-threatening condition, and is characterized by disseminated intravascular coagulation and skin necrosis. It is a morbid and potentially fatal condition that can be a cutaneous manifestation of Morganella morganii bacteraemia. Early identification and accurate diagnosis of the underlying cause can help minimize morbidity and mortality; management should be tailored to the individual, with the use of intravenous antibiotics, necrotic skin excision and aggressive early resuscitation. SMC Media Srl 2022-11-21 /pmc/articles/PMC9728211/ /pubmed/36506741 http://dx.doi.org/10.12890/2022_003670 Text en © EFIM 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Articles
Guerra, Mariana
Marado, Daniela
Fulminans Purpura due to Morganella morganii
title Fulminans Purpura due to Morganella morganii
title_full Fulminans Purpura due to Morganella morganii
title_fullStr Fulminans Purpura due to Morganella morganii
title_full_unstemmed Fulminans Purpura due to Morganella morganii
title_short Fulminans Purpura due to Morganella morganii
title_sort fulminans purpura due to morganella morganii
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728211/
https://www.ncbi.nlm.nih.gov/pubmed/36506741
http://dx.doi.org/10.12890/2022_003670
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