BCL11B depletion induces the development of highly cytotoxic innate T cells out of IL-15 stimulated peripheral blood αβ CD8+ T cells

BCL11B, an essential transcription factor for thymopoiesis, regulates also vital processes in post-thymic lymphocytes. Increased expression of BCL11B was recently correlated with the maturation of NK cells, whereas reduced BCL11B levels were observed in native and induced T cell subsets displaying N...

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Detalles Bibliográficos
Autores principales: Forkel, Hannes, Grabarczyk, Piotr, Depke, Maren, Troschke-Meurer, Sascha, Simm, Stefan, Hammer, Elke, Michalik, Stephan, Hentschker, Christian, Corleis, Björn, Loyal, Lucie, Zumpe, Maxi, Siebert, Nikolai, Dorhoi, Anca, Thiel, Andreas, Lode, Holger, Völker, Uwe, Schmidt, Christian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728472/
https://www.ncbi.nlm.nih.gov/pubmed/36507091
http://dx.doi.org/10.1080/2162402X.2022.2148850

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