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Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients

INTRODUCTION: Restoration of immune tolerance may halt progression of autoimmune diseases. Tolerogenic dendritic cells (tolDC) inhibit antigen-specific proinflammatory T-cells, generate antigen-specific regulatory T-cells and promote IL-10 production in-vitro, providing an appealing immunotherapy to...

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Detalles Bibliográficos
Autores principales:	Nikolic, Tatjana, Suwandi, Jessica S., Wesselius, Joris, Laban, Sandra, Joosten, Antoinette M., Sonneveld, Petra, Mul, Dick, Aanstoot, Henk-Jan, Kaddis, John S., Zwaginga, Jaap Jan, Roep, Bart O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728525/ https://www.ncbi.nlm.nih.gov/pubmed/36505460 http://dx.doi.org/10.3389/fimmu.2022.1054968

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