Chiral derivatization-enabled discrimination and on-tissue detection of proteinogenic amino acids by ion mobility mass spectrometry

The importance of chiral amino acids (AAs) in living organisms has been widely recognized since the discovery of endogenous d-AAs as potential biomarkers in several metabolic disorders. Chiral analysis by ion mobility spectrometry-mass spectrometry (IMS-MS) has the advantages of high speed and sensi...

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Detalles Bibliográficos
Autores principales: Xie, Chengyi, Chen, Yanyan, Wang, Xiaoxiao, Song, Yuanyuan, Shen, Yuting, Diao, Xin, Zhu, Lin, Wang, Jianing, Cai, Zongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728562/
https://www.ncbi.nlm.nih.gov/pubmed/36540812
http://dx.doi.org/10.1039/d2sc03604e