Cargando…

Epidemiology of Vitamin D (EpiVida)—A Study of Vitamin D Status Among Healthy Adults in Brazil

CONTEXT: There are few studies of 25-hydroxyvitamin D (25(OH)D) concentrations in healthy adults in Brazil. OBJECTIVE: This work aimed to estimate the prevalence of vitamin D status and its association with lifestyle, sociodemographic, and anthropometric data in 3 regions of Brazil. METHODS: A cross...

Descripción completa

Detalles Bibliográficos
Autores principales: Borba, Victoria Zeghbi Cochenski, Lazaretti-Castro, Marise, Moreira, Sandra da Silva, de Almeida, Maria Conceição Chagas, Moreira, Edson Duarte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728789/
https://www.ncbi.nlm.nih.gov/pubmed/36518902
http://dx.doi.org/10.1210/jendso/bvac171
_version_ 1784845339083145216
author Borba, Victoria Zeghbi Cochenski
Lazaretti-Castro, Marise
Moreira, Sandra da Silva
de Almeida, Maria Conceição Chagas
Moreira, Edson Duarte
author_facet Borba, Victoria Zeghbi Cochenski
Lazaretti-Castro, Marise
Moreira, Sandra da Silva
de Almeida, Maria Conceição Chagas
Moreira, Edson Duarte
author_sort Borba, Victoria Zeghbi Cochenski
collection PubMed
description CONTEXT: There are few studies of 25-hydroxyvitamin D (25(OH)D) concentrations in healthy adults in Brazil. OBJECTIVE: This work aimed to estimate the prevalence of vitamin D status and its association with lifestyle, sociodemographic, and anthropometric data in 3 regions of Brazil. METHODS: A cross-sectional study was conducted among blood donors of both sexes, living in the cities of Salvador, São Paulo, and Curitiba during summer. Blood samples were collected during the procedure. Serum 25(OH)D and parathyroid hormone (PTH) were measured in the same laboratory using chemiluminescence immunoassays. Lifestyle, sociodemographic, and anthropometric data were gathered by an interview with a standardized questionnaire. Vitamin D deficiency and insufficiency was defined as 25(OH)D levels below 20 ng/mL and below 30 ng/mL, respectively. RESULTS: A total of 1004 healthy adults were evaluated with mean levels of 25(OH)D (28.7 ± 9.27 ng/mL) and PTH (34.4 ± 15.1 pg/mL). The standardized prevalence of vitamin D deficiency and insufficiency was in the study population 15.3% and 50.9%: in Salvador 12.1% and 47.6%, in São Paulo 20.5%, and 52.4% and in Curitiba 12.7% and 52.1%, (P = .0004). PTH levels were negatively correlated with 25(OH)D levels. Greater body mass index (BMI) and higher latitude were significant predictors of vitamin D deficiency, whereas skin color (White), longer duration of sun exposure, and current use of dietary supplement were protective. CONCLUSION: This study confirmed the high prevalence of vitamin D deficiency and insufficiency even in the midsummer in a healthy population of Brazil. Vitamin D levels are associated with sun exposure, latitude, BMI, skin color, and use of supplements.
format Online
Article
Text
id pubmed-9728789
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-97287892022-12-13 Epidemiology of Vitamin D (EpiVida)—A Study of Vitamin D Status Among Healthy Adults in Brazil Borba, Victoria Zeghbi Cochenski Lazaretti-Castro, Marise Moreira, Sandra da Silva de Almeida, Maria Conceição Chagas Moreira, Edson Duarte J Endocr Soc Clinical Research Article CONTEXT: There are few studies of 25-hydroxyvitamin D (25(OH)D) concentrations in healthy adults in Brazil. OBJECTIVE: This work aimed to estimate the prevalence of vitamin D status and its association with lifestyle, sociodemographic, and anthropometric data in 3 regions of Brazil. METHODS: A cross-sectional study was conducted among blood donors of both sexes, living in the cities of Salvador, São Paulo, and Curitiba during summer. Blood samples were collected during the procedure. Serum 25(OH)D and parathyroid hormone (PTH) were measured in the same laboratory using chemiluminescence immunoassays. Lifestyle, sociodemographic, and anthropometric data were gathered by an interview with a standardized questionnaire. Vitamin D deficiency and insufficiency was defined as 25(OH)D levels below 20 ng/mL and below 30 ng/mL, respectively. RESULTS: A total of 1004 healthy adults were evaluated with mean levels of 25(OH)D (28.7 ± 9.27 ng/mL) and PTH (34.4 ± 15.1 pg/mL). The standardized prevalence of vitamin D deficiency and insufficiency was in the study population 15.3% and 50.9%: in Salvador 12.1% and 47.6%, in São Paulo 20.5%, and 52.4% and in Curitiba 12.7% and 52.1%, (P = .0004). PTH levels were negatively correlated with 25(OH)D levels. Greater body mass index (BMI) and higher latitude were significant predictors of vitamin D deficiency, whereas skin color (White), longer duration of sun exposure, and current use of dietary supplement were protective. CONCLUSION: This study confirmed the high prevalence of vitamin D deficiency and insufficiency even in the midsummer in a healthy population of Brazil. Vitamin D levels are associated with sun exposure, latitude, BMI, skin color, and use of supplements. Oxford University Press 2022-11-09 /pmc/articles/PMC9728789/ /pubmed/36518902 http://dx.doi.org/10.1210/jendso/bvac171 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Clinical Research Article
Borba, Victoria Zeghbi Cochenski
Lazaretti-Castro, Marise
Moreira, Sandra da Silva
de Almeida, Maria Conceição Chagas
Moreira, Edson Duarte
Epidemiology of Vitamin D (EpiVida)—A Study of Vitamin D Status Among Healthy Adults in Brazil
title Epidemiology of Vitamin D (EpiVida)—A Study of Vitamin D Status Among Healthy Adults in Brazil
title_full Epidemiology of Vitamin D (EpiVida)—A Study of Vitamin D Status Among Healthy Adults in Brazil
title_fullStr Epidemiology of Vitamin D (EpiVida)—A Study of Vitamin D Status Among Healthy Adults in Brazil
title_full_unstemmed Epidemiology of Vitamin D (EpiVida)—A Study of Vitamin D Status Among Healthy Adults in Brazil
title_short Epidemiology of Vitamin D (EpiVida)—A Study of Vitamin D Status Among Healthy Adults in Brazil
title_sort epidemiology of vitamin d (epivida)—a study of vitamin d status among healthy adults in brazil
topic Clinical Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728789/
https://www.ncbi.nlm.nih.gov/pubmed/36518902
http://dx.doi.org/10.1210/jendso/bvac171
work_keys_str_mv AT borbavictoriazeghbicochenski epidemiologyofvitamindepividaastudyofvitamindstatusamonghealthyadultsinbrazil
AT lazaretticastromarise epidemiologyofvitamindepividaastudyofvitamindstatusamonghealthyadultsinbrazil
AT moreirasandradasilva epidemiologyofvitamindepividaastudyofvitamindstatusamonghealthyadultsinbrazil
AT dealmeidamariaconceicaochagas epidemiologyofvitamindepividaastudyofvitamindstatusamonghealthyadultsinbrazil
AT moreiraedsonduarte epidemiologyofvitamindepividaastudyofvitamindstatusamonghealthyadultsinbrazil