Overcoming the cytoplasmic retention of GDOWN1 modulates global transcription and facilitates stress adaptation

Dynamic regulation of transcription is crucial for the cellular responses to various environmental or developmental cues. Gdown1 is a ubiquitously expressed, RNA polymerase II (Pol II) interacting protein, essential for the embryonic development of metazoan. It tightly binds Pol II in vitro and comp...

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Detalles Bibliográficos
Autores principales: Zhu, Zhanwu, Liu, Jingjing, Feng, Huan, Zhang, Yanning, Huang, Ruiqi, Pan, Qiaochu, Nan, Jing, Miao, Ruidong, Cheng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728996/
https://www.ncbi.nlm.nih.gov/pubmed/36476745
http://dx.doi.org/10.7554/eLife.79116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728996/
https://www.ncbi.nlm.nih.gov/pubmed/36476745
http://dx.doi.org/10.7554/eLife.79116

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