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Multiparametric and accurate functional analysis of genetic sequence variants using CRISPR-Select
Determining the functional role of thousands of genetic sequence variants (mutations) associated with genetic diseases is a major challenge. Here we present clustered regularly interspaced short palindromic repeat (CRISPR)-Select(TIME), CRISPR-Select(SPACE) and CRISPR-Select(STATE), a set of flexibl...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729100/ https://www.ncbi.nlm.nih.gov/pubmed/36471068 http://dx.doi.org/10.1038/s41588-022-01224-7 |