Autoantibody and T cell responses to oxidative post-translationally modified insulin neoantigenic peptides in type 1 diabetes

AIMS/HYPOTHESIS: Antibodies specific to oxidative post-translational modifications (oxPTM) of insulin (oxPTM-INS) are present in most individuals with type 1 diabetes, even before the clinical onset. However, the antigenic determinants of such response are still unknown. In this study, we investigat...

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Detalles Bibliográficos
Autores principales: Strollo, Rocky, Vinci, Chiara, Man, Y. K. Stella, Bruzzaniti, Sara, Piemonte, Erica, Alhamar, Ghadeer, Briganti, Silvia Irina, Malandrucco, Ilaria, Tramontana, Flavia, Fanali, Chiara, Garnett, James, Buccafusca, Roberto, Guyer, Perrin, Mamula, Mark, James, Eddie A., Pozzilli, Paolo, Ludvigsson, Johnny, Winyard, Paul G., Galgani, Mario, Nissim, Ahuva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729141/
https://www.ncbi.nlm.nih.gov/pubmed/36207582
http://dx.doi.org/10.1007/s00125-022-05812-4

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