Cargando…

Rapid induction and long-term self-renewal of neural crest-derived ectodermal chondrogenic cells from hPSCs

Articular cartilage is highly specific and has limited capacity for regeneration if damaged. Human pluripotent stem cells (hPSCs) have the potential to generate any cell type in the body. Here, we report the dual-phase induction of ectodermal chondrogenic cells (ECCs) from hPSCs through the neural c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Pei, Chen, Lu, Zhang, Dahe, Xia, Simo, Lv, Zhuman, Zou, Duohong, Zhang, Zhiyuan, Yang, Chi, Li, Wenlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729200/ https://www.ncbi.nlm.nih.gov/pubmed/36477591 http://dx.doi.org/10.1038/s41536-022-00265-0

Ejemplares similares

Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions
por: Hackland, James O.S., et al.
Publicado: (2017)

Endothelial and hematopoietic hPSCs differentiation via a hematoendothelial progenitor
por: Vargas-Valderrama, Alejandra, et al.
Publicado: (2022)

PINE-TREE enables efficient enrichment of prime-edited hPSCs
por: Jia, Mary S., et al.
Publicado: (2023)

Maintenance of hPSCs under Xeno-Free and Chemically Defined Culture Conditions
por: Lim, Jung Jin, et al.
Publicado: (2019)

ESRG is critical to maintain the cell survival and self-renewal/pluripotency of hPSCs by collaborating with MCM2 to suppress p53 pathway
por: Li, Shasha, et al.
Publicado: (2023)

Generation of caudal-type serotonin neurons and hindbrain-fate organoids from hPSCs
por: Valiulahi, Parvin, et al.
Publicado: (2021)

Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome
por: Zhu, Wenliang, et al.
Publicado: (2019)

Mapping germ-layer specification preventing genes in hPSCs via genome-scale CRISPR screening
por: Xu, Xiangjie, et al.
Publicado: (2020)

Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development
por: Shi, Zhong-Dong, et al.
Publicado: (2017)

Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation
por: Teo, Adrian Kee Keong, et al.
Publicado: (2021)

MSX2 Initiates and Accelerates Mesenchymal Stem/Stromal Cell Specification of hPSCs by Regulating TWIST1 and PRAME
por: Zhang, Leisheng, et al.
Publicado: (2018)

Protocol for genome-scale CRISPR screening in engineered lineage reporter hPSCs to study cell fate determination
por: Zhou, Zhongshu, et al.
Publicado: (2021)

Effective derivation of ventricular cardiomyocytes from hPSCs using ascorbic acid-containing maturation medium
por: Kim, Ji-eun, et al.
Publicado: (2023)

Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma
por: Samuel, Ryan M., et al.
Publicado: (2023)

SIX1(+)PAX3(+) identify a progenitor for myogenic lineage commitment from hPSCs
por: Jaime, Olga G., et al.
Publicado: (2023)

Single-cell qPCR facilitates the optimization of hematopoietic differentiation in hPSCs/OP9 coculture system
por: Chen, Haide, et al.
Publicado: (2018)

miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro
por: Ishikawa, Mitsuru, et al.
Publicado: (2020)

Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs
por: Bertero, Alessandro, et al.
Publicado: (2016)

De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
por: Motosugi, Nami, et al.
Publicado: (2022)

Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors
por: Smith, Christopher A., et al.
Publicado: (2023)

Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification
por: Maurya, Shailendra, et al.
Publicado: (2021)

Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells
por: Xu, He Jax, et al.
Publicado: (2023)

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
por: Ordovás, Laura, et al.
Publicado: (2015)

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
por: Ordovás, Laura, et al.
Publicado: (2018)

Maintenance of pluripotency in the entire ectoderm enables neural crest formation
por: Pajanoja, Ceren, et al.
Publicado: (2023)

Standardization of Cell Culture Conditions and Routine Genomic Screening under a Quality Management System Leads to Reduced Genomic Instability in hPSCs
por: Molina-Ruiz, Francisco J., et al.
Publicado: (2022)

Induction of Neural Crest Stem Cells From Bardet–Biedl Syndrome Patient Derived hiPSCs
por: Barrell, William B., et al.
Publicado: (2019)

Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs
por: Qu, Ying, et al.
Publicado: (2016)

Symmetry Breaking of Human Pluripotent Stem Cells (hPSCs) in Micropattern Generates a Polarized Spinal Cord‐Like Organoid (pSCO) with Dorsoventral Organization
por: Seo, Kyubin, et al.
Publicado: (2023)

Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage
por: Kamiya, Daisuke, et al.
Publicado: (2022)

Maintenance of pluripotency-like signature in the entire ectoderm leads to neural crest stem cell potential
por: Pajanoja, Ceren, et al.
Publicado: (2023)

Cord blood cell-derived iPSCs as a new candidate for chondrogenic differentiation and cartilage regeneration
por: Nam, Yoojun, et al.
Publicado: (2017)

A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development
por: Rouleau, Michèle, et al.
Publicado: (2011)

Chondrogenic and Gliogenic Subpopulations of Neural Crest Play Distinct Roles during the Assembly of Epibranchial Ganglia
por: Culbertson, Maya D., et al.
Publicado: (2011)

Enhanced chondrogenic differentiation of iPS cell-derived mesenchymal stem/stromal cells via neural crest cell induction for hyaline cartilage repair
por: Zujur, Denise, et al.
Publicado: (2023)

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates
por: Plouhinec, Jean-Louis, et al.
Publicado: (2017)

Status of KRAS in iPSCs Impacts upon Self-Renewal and Differentiation Propensity
por: Kubara, Kenji, et al.
Publicado: (2018)

Modeling cartilage pathology in mucopolysaccharidosis VI using iPSCs reveals early dysregulation of chondrogenic and metabolic gene expression
por: Broeders, M., et al.
Publicado: (2022)

Epigenetic Modifiers Facilitate Induction and Pluripotency of Porcine iPSCs
por: Mao, Jian, et al.
Publicado: (2016)

Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response
por: Qi, Yan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gu858280l0n0oh3im4rfokfu14