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Deep learning classification of urinary sediment crystals with optimal parameter tuning

The examination of urinary sediment crystals, the sedimentary components of urine, is useful in screening tests, and is always performed in medical examinations. The examination of urinary sediment crystals is typically done by classifying them under a microscope. Although automated analyzers are co...

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Autores principales: Nagai, Takahiro, Onodera, Osamu, Okuda, Shujiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729224/
https://www.ncbi.nlm.nih.gov/pubmed/36477082
http://dx.doi.org/10.1038/s41598-022-25385-x
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author Nagai, Takahiro
Onodera, Osamu
Okuda, Shujiro
author_facet Nagai, Takahiro
Onodera, Osamu
Okuda, Shujiro
author_sort Nagai, Takahiro
collection PubMed
description The examination of urinary sediment crystals, the sedimentary components of urine, is useful in screening tests, and is always performed in medical examinations. The examination of urinary sediment crystals is typically done by classifying them under a microscope. Although automated analyzers are commercially available, manual classification is required, which is time-consuming and varies depending on the technologist performing the test and the laboratory. A set of test images was created, consisting of training, validation, and test images. The training images were transformed and augmented using various methods. The test images were classified to determine the patterns that could be correctly classified. Convolutional neural networks were used for training. Furthermore, we also considered the case where the crystal subcategories were not treated as separate. Learning with all parameters except the random cropping parameter showed the highest accuracy value. Treating the subcategories together or separately did not seem to affect the accuracy value. The accuracy of the best pattern was 0.918. When matched to a real-world case, the percentage of correct answers was 88%. Although the number of images was limited, good results were obtained in the classification of crystal images with optimal parameter tuning. The parameter optimization performed in this study can be used as a reference for future studies, with the goal of image classification by deep learning in clinical practice.
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spelling pubmed-97292242022-12-09 Deep learning classification of urinary sediment crystals with optimal parameter tuning Nagai, Takahiro Onodera, Osamu Okuda, Shujiro Sci Rep Article The examination of urinary sediment crystals, the sedimentary components of urine, is useful in screening tests, and is always performed in medical examinations. The examination of urinary sediment crystals is typically done by classifying them under a microscope. Although automated analyzers are commercially available, manual classification is required, which is time-consuming and varies depending on the technologist performing the test and the laboratory. A set of test images was created, consisting of training, validation, and test images. The training images were transformed and augmented using various methods. The test images were classified to determine the patterns that could be correctly classified. Convolutional neural networks were used for training. Furthermore, we also considered the case where the crystal subcategories were not treated as separate. Learning with all parameters except the random cropping parameter showed the highest accuracy value. Treating the subcategories together or separately did not seem to affect the accuracy value. The accuracy of the best pattern was 0.918. When matched to a real-world case, the percentage of correct answers was 88%. Although the number of images was limited, good results were obtained in the classification of crystal images with optimal parameter tuning. The parameter optimization performed in this study can be used as a reference for future studies, with the goal of image classification by deep learning in clinical practice. Nature Publishing Group UK 2022-12-07 /pmc/articles/PMC9729224/ /pubmed/36477082 http://dx.doi.org/10.1038/s41598-022-25385-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Nagai, Takahiro
Onodera, Osamu
Okuda, Shujiro
Deep learning classification of urinary sediment crystals with optimal parameter tuning
title Deep learning classification of urinary sediment crystals with optimal parameter tuning
title_full Deep learning classification of urinary sediment crystals with optimal parameter tuning
title_fullStr Deep learning classification of urinary sediment crystals with optimal parameter tuning
title_full_unstemmed Deep learning classification of urinary sediment crystals with optimal parameter tuning
title_short Deep learning classification of urinary sediment crystals with optimal parameter tuning
title_sort deep learning classification of urinary sediment crystals with optimal parameter tuning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729224/
https://www.ncbi.nlm.nih.gov/pubmed/36477082
http://dx.doi.org/10.1038/s41598-022-25385-x
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