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Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression

Interleukin 1α (IL-1α) and IL-1β are the founding members of the IL-1 cytokine family, and these innate immune inflammatory mediators are critically important in health and disease. Early studies on these molecules suggested that their expression was interdependent, with an initial genetic model of...

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Detalles Bibliográficos
Autores principales:	Malireddi, R.K. Subbarao, Bynigeri, Ratnakar R., Kancharana, Balabhaskararao, Sharma, Bhesh Raj, Burton, Amanda R., Pelletier, Stephane, Kanneganti, Thirumala-Devi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729281/ https://www.ncbi.nlm.nih.gov/pubmed/36505497 http://dx.doi.org/10.3389/fimmu.2022.1068230

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