Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin A

Precision oncology research is challenging outside the contexts of oncogenic addiction and/or targeted therapies. We previously showed that phosphoproteomics is a powerful approach to reveal patient subsets of interest characterized by the activity of a few kinases where the underlying genomics is c...

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Detalles Bibliográficos
Autores principales: Mouron, S., Bueno, M. J., Lluch, A., Manso, L., Calvo, I., Cortes, J., Garcia-Saenz, J. A., Gil-Gil, M., Martinez-Janez, N., Apala, J. V., Caleiras, E., Ximénez-Embún, Pilar, Muñoz, J., Gonzalez-Cortijo, L., Murillo, R., Sánchez-Bayona, R., Cejalvo, J. M., Gómez-López, G., Fustero-Torre, C., Sabroso-Lasa, S., Malats, N., Martinez, M., Moreno, A., Megias, D., Malumbres, M., Colomer, R., Quintela-Fandino, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729295/
https://www.ncbi.nlm.nih.gov/pubmed/36477027
http://dx.doi.org/10.1038/s41467-022-35065-z

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