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Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global public health crisis. The reduced efficacy of therapeutic monoclonal antibodies against emerging SARS-CoV-2 variants of concern (VOCs), such as omicron BA.5 subvariants, has underlined the...

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Detalles Bibliográficos
Autores principales: Pérez-Vargas, Jimena, Shapira, Tirosh, Olmstead, Andrea D., Villanueva, Ivan, Thompson, Connor A.H., Ennis, Siobhan, Gao, Guang, De Guzman, Joshua, Williams, David E., Wang, Meng, Chin, Aaleigha, Bautista-Sánchez, Diana, Agafitei, Olga, Levett, Paul, Xie, Xuping, Nuzzo, Genoveffa, Freire, Vitor F., Quintana-Bulla, Jairo I., Bernardi, Darlon I., Gubiani, Juliana R., Suthiphasilp, Virayu, Raksat, Achara, Meesakul, Pornphimol, Polbuppha, Isaraporn, Cheenpracha, Sarot, Jaidee, Wuttichai, Kanokmedhakul, Kwanjai, Yenjai, Chavi, Chaiyosang, Boonyanoot, Teles, Helder Lopes, Manzo, Emiliano, Fontana, Angelo, Leduc, Richard, Boudreault, Pierre-Luc, Berlinck, Roberto G.S., Laphookhieo, Surat, Kanokmedhakul, Somdej, Tietjen, Ian, Cherkasov, Artem, Krajden, Mel, Nabi, Ivan Robert, Niikura, Masahiro, Shi, Pei-Yong, Andersen, Raymond J., Jean, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729583/
https://www.ncbi.nlm.nih.gov/pubmed/36503013
http://dx.doi.org/10.1016/j.antiviral.2022.105484