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Age-associated B cells are long-lasting effectors that impede latent γHV68 reactivation

Age-associated B cells (ABCs; CD19(+)CD11c(+)T-bet(+)) are a unique population that are increased in an array of viral infections, though their role during latent infection is largely unexplored. Here, we use murine gammaherpesvirus 68 (γHV68) to demonstrate that ABCs remain elevated long-term durin...

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Detalles Bibliográficos
Autores principales: Mouat, Isobel C., Shanina, Iryna, Horwitz, Marc S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729602/
https://www.ncbi.nlm.nih.gov/pubmed/36477199
http://dx.doi.org/10.1038/s41598-022-25543-1