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Implications of differential peroxyl radical-induced inactivation of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase for the pentose phosphate pathway

Escherichia coli glucose-6-phosphate dehydrogenase (G6PDH) and 6-phosphogluconate dehydrogenase (6PGDH) are key enzymes of the pentose phosphate pathway, responsible for the NADPH production in cells. We investigated modification of both enzymes mediated by peroxyl radicals (ROO(·)) to determine the...

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Detalles Bibliográficos
Autores principales:	Reyes, Juan Sebastián, Fuentes-Lemus, Eduardo, Figueroa, Juan David, Rojas, Javier, Fierro, Angélica, Arenas, Felipe, Hägglund, Per M., Davies, Michael J., López-Alarcón, Camilo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729611/ https://www.ncbi.nlm.nih.gov/pubmed/36476946 http://dx.doi.org/10.1038/s41598-022-25474-x

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