Cargando…
Direct thrombin inhibitors as alternatives to heparin to preserve lung growth and function in a murine model of compensatory lung growth
Infants with congenital diaphragmatic hernia (CDH) may require cardiopulmonary bypass and systemic anticoagulation. Expeditious lung growth while on bypass is essential for survival. Previously, we demonstrated that heparin impairs lung growth and function in a murine model of compensatory lung grow...
Autores principales: | Tsikis, Savas T., Hirsch, Thomas I., Fligor, Scott C., Pan, Amy, Joiner, Malachi M., Devietro, Angela, Mitchell, Paul D., Kishikawa, Hiroko, Gura, Kathleen M., Puder, Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729628/ https://www.ncbi.nlm.nih.gov/pubmed/36477689 http://dx.doi.org/10.1038/s41598-022-25773-3 |
Ejemplares similares
-
A pneumonectomy model to study flow-induced pulmonary hypertension and compensatory lung growth
por: Tsikis, Savas T., et al.
Publicado: (2023) -
Lipopolysaccharide-induced murine lung injury results in long-term pulmonary changes and downregulation of angiogenic pathways
por: Tsikis, S. T., et al.
Publicado: (2022) -
Investigation of the mechanisms of VEGF-mediated compensatory lung growth: the role of the VEGF heparin-binding domain
por: Yu, Lumeng J., et al.
Publicado: (2021) -
Targeting the lung endothelial niche to promote angiogenesis and regeneration: A review of applications
por: Tsikis, Savas T., et al.
Publicado: (2022) -
Vascular Endothelial Growth Factor Accelerates Compensatory Lung Growth by Increasing Alveolar Units
por: Dao, Duy T., et al.
Publicado: (2018)