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The effect of food on the pharmacokinetics of WXFL10203614, a potential selective JAK1 inhibitor, in healthy Chinese subjects

Objective: This study was performed to investigate the effect of food on the pharmacokinetics (PK) of WXFL10203614 in healthy Chinese subjects. Methods: This was a randomized, open-label, single-dose, two-treatment (fed vs fasted), two-period, two-sequence, crossover study. 14 eligible subjects were...

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Detalles Bibliográficos
Autores principales: Huang, Kai, Shi, Yunfei, Chu, Nannan, Que, Linling, Ding, Ying, Qian, Zhenzhong, Qin, Wei, Gu, Xianghong, Wang, Jiakun, Zhang, Zhiwei, Xu, Jianguo, He, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729727/
https://www.ncbi.nlm.nih.gov/pubmed/36506530
http://dx.doi.org/10.3389/fphar.2022.1066895