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A Case Report of a Sacral Giant Cell Tumor Treated With Block Resection and Lumbo-Pelvic Fixation

Giant cell tumors (GCT) are benign but locally aggressive neoplasms composed of osteoclast-like giant cells and fusiform to ovoid mononuclear stromal cells. GCT generally comprise 5-10% of all benign bone tumors; they appear most frequently between the second and third decades of life. These tumors...

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Autores principales: Hernandez, Carlos L, Díaz, Salvador M, Nurmukhametov, Renat, Goncharov, Evgeny, Ramirez, Manuel de Jesus Encarnacion, Bozkurt, Ismail, Ramirez Pena, Issael Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729751/
https://www.ncbi.nlm.nih.gov/pubmed/36505101
http://dx.doi.org/10.7759/cureus.31224
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author Hernandez, Carlos L
Díaz, Salvador M
Nurmukhametov, Renat
Goncharov, Evgeny
Ramirez, Manuel de Jesus Encarnacion
Bozkurt, Ismail
Ramirez Pena, Issael Jesus
author_facet Hernandez, Carlos L
Díaz, Salvador M
Nurmukhametov, Renat
Goncharov, Evgeny
Ramirez, Manuel de Jesus Encarnacion
Bozkurt, Ismail
Ramirez Pena, Issael Jesus
author_sort Hernandez, Carlos L
collection PubMed
description Giant cell tumors (GCT) are benign but locally aggressive neoplasms composed of osteoclast-like giant cells and fusiform to ovoid mononuclear stromal cells. GCT generally comprise 5-10% of all benign bone tumors; they appear most frequently between the second and third decades of life. These tumors are also distributed throughout the vertebral column. Approximately half of all spinal GTCs develop in the sacrum. Many cases remain clinically silent and are discovered incidentally during the study of minor trauma. Symptomatic tumors often mimic other common spinal pathologies. Imaging studies ideal for diagnosis are CT and MRI. The techniques used in the treatment of giant cell tumors are curettage or intralesional surgery, block resection, radiotherapy, and chemotherapy. Herein, we report on a 23-year-old female patient diagnosed with a tumoral mass in the anterior part of the sacrum, suggestive of GCT. The lesion was completely excised in two consecutive surgeries, and lumbopelvic fixation was performed with favorable immediate postoperative results. Careful surgical planning with a multi-disciplinary approach leading to block resection still remains the most viable option for the treatment of vertebral GCT.
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spelling pubmed-97297512022-12-08 A Case Report of a Sacral Giant Cell Tumor Treated With Block Resection and Lumbo-Pelvic Fixation Hernandez, Carlos L Díaz, Salvador M Nurmukhametov, Renat Goncharov, Evgeny Ramirez, Manuel de Jesus Encarnacion Bozkurt, Ismail Ramirez Pena, Issael Jesus Cureus Neurosurgery Giant cell tumors (GCT) are benign but locally aggressive neoplasms composed of osteoclast-like giant cells and fusiform to ovoid mononuclear stromal cells. GCT generally comprise 5-10% of all benign bone tumors; they appear most frequently between the second and third decades of life. These tumors are also distributed throughout the vertebral column. Approximately half of all spinal GTCs develop in the sacrum. Many cases remain clinically silent and are discovered incidentally during the study of minor trauma. Symptomatic tumors often mimic other common spinal pathologies. Imaging studies ideal for diagnosis are CT and MRI. The techniques used in the treatment of giant cell tumors are curettage or intralesional surgery, block resection, radiotherapy, and chemotherapy. Herein, we report on a 23-year-old female patient diagnosed with a tumoral mass in the anterior part of the sacrum, suggestive of GCT. The lesion was completely excised in two consecutive surgeries, and lumbopelvic fixation was performed with favorable immediate postoperative results. Careful surgical planning with a multi-disciplinary approach leading to block resection still remains the most viable option for the treatment of vertebral GCT. Cureus 2022-11-07 /pmc/articles/PMC9729751/ /pubmed/36505101 http://dx.doi.org/10.7759/cureus.31224 Text en Copyright © 2022, Hernandez et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurosurgery
Hernandez, Carlos L
Díaz, Salvador M
Nurmukhametov, Renat
Goncharov, Evgeny
Ramirez, Manuel de Jesus Encarnacion
Bozkurt, Ismail
Ramirez Pena, Issael Jesus
A Case Report of a Sacral Giant Cell Tumor Treated With Block Resection and Lumbo-Pelvic Fixation
title A Case Report of a Sacral Giant Cell Tumor Treated With Block Resection and Lumbo-Pelvic Fixation
title_full A Case Report of a Sacral Giant Cell Tumor Treated With Block Resection and Lumbo-Pelvic Fixation
title_fullStr A Case Report of a Sacral Giant Cell Tumor Treated With Block Resection and Lumbo-Pelvic Fixation
title_full_unstemmed A Case Report of a Sacral Giant Cell Tumor Treated With Block Resection and Lumbo-Pelvic Fixation
title_short A Case Report of a Sacral Giant Cell Tumor Treated With Block Resection and Lumbo-Pelvic Fixation
title_sort case report of a sacral giant cell tumor treated with block resection and lumbo-pelvic fixation
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729751/
https://www.ncbi.nlm.nih.gov/pubmed/36505101
http://dx.doi.org/10.7759/cureus.31224
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