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Identifying inflammatory phenotypes to target mechanism-specific treatments in sepsis
A clinical trial by Leventogiannis et al.(1) suggests that ferritin and HLA-DR monocyte receptor expression can identify septic patients with macrophage-activation-like syndrome (MALS), or immunoparalysis, and that targeting IL-1ra treatment with this strategy may improve outcomes.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729868/ https://www.ncbi.nlm.nih.gov/pubmed/36384087 http://dx.doi.org/10.1016/j.xcrm.2022.100823 |