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Tumor glycolytic profiling through (18)F-FDG PET/CT predicts immune checkpoint inhibitor efficacy in advanced NSCLC
BACKGROUND: A significant proportion of patients with non-small-cell lung cancer (NSCLC) do not respond to immune checkpoint inhibitors (ICIs). Since metabolic reprogramming with increased glycolysis is a hallmark of cancer and is involved in immune evasion, we used (18)F-fluorodeoxyglucose positron...
Autores principales: | Silva, Saulo Brito, Wanderley, Carlos Wagner S., Gomes Marin, José Flavio, de Macedo, Mariana Petaccia, do Nascimento, Ellen Caroline Toledo, Antonacio, Fernanda Frozoni, Figueiredo, Caroline Sales, Trinconi Cunha, Mateus, Cunha, Fernando Q., de Castro Junior, Gilberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730014/ https://www.ncbi.nlm.nih.gov/pubmed/36506107 http://dx.doi.org/10.1177/17588359221138386 |
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