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Single-cell transcriptomics in bone marrow delineates CD56(dim)GranzymeK(+) subset as intermediate stage in NK cell differentiation

Human natural killer (NK) cells in lymphoid tissues can be categorized into three subsets: CD56(bright)CD16(+), CD56(dim)CD16(+) and CD69(+)CXCR6(+) lymphoid tissue-resident (lt)NK cells. How the three subsets are functionally and developmentally related is currently unknown. Therefore, we performed...

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Detalles Bibliográficos
Autores principales:	Melsen, Janine E., van Ostaijen-ten Dam, Monique M., Schoorl, Dorenda J. A., Schol, Pieter J., van den Homberg, Daphne A. L., Lankester, Arjan C., Lugthart, Gertjan, Schilham, Marco W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730327/ https://www.ncbi.nlm.nih.gov/pubmed/36505452 http://dx.doi.org/10.3389/fimmu.2022.1044398

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