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Computational model of CAR T-cell immunotherapy dissects and predicts leukemia patient responses at remission, resistance, and relapse

BACKGROUND: Adaptive CD19-targeted chimeric antigen receptor (CAR) T-cell transfer has become a promising treatment for leukemia. Although patient responses vary across different clinical trials, reliable methods to dissect and predict patient responses to novel therapies are currently lacking. Rece...

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Detalles Bibliográficos
Autores principales:	Liu, Lunan, Ma, Chao, Zhang, Zhuoyu, Witkowski, Matthew T, Aifantis, Iannis, Ghassemi, Saba, Chen, Weiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730379/ https://www.ncbi.nlm.nih.gov/pubmed/36600553 http://dx.doi.org/10.1136/jitc-2022-005360

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