Mitotic phosphorylation inhibits the Golgi mannosidase MAN1A1

N-glycans are processed mainly in the Golgi, and a well-organized Golgi structure is required for accurate glycosylation. However, during mitosis the Golgi undergoes severe fragmentation. The resulting trafficking block leads to an extended exposure of cargo molecules to Golgi enzymes. It is unclear...

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Detalles Bibliográficos
Autores principales: Huang, Shijiao, Haga, Yoshimi, Li, Jie, Zhang, Jianchao, Kweon, Hye Kyong, Seino, Junichi, Hirayama, Hiroto, Fujita, Morihisa, Moremen, Kelley W., Andrews, Philip, Suzuki, Tadashi, Wang, Yanzhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730451/
https://www.ncbi.nlm.nih.gov/pubmed/36417860
http://dx.doi.org/10.1016/j.celrep.2022.111679

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