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Evidence of Filamin A loss of solubility at the prodromal stage of neuropathologically-defined Alzheimer’s disease

INTRODUCTION: Alzheimer’s disease (AD) is a multifactorial disorder diagnosed through the assessment of amyloid-beta (Aβ) and tau protein depositions. Filamin A (FLNA) could be a key partner of both Aβ and tau pathological processes and may be an important contributor to AD progression. The main aim...

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Detalles Bibliográficos
Autores principales: Aumont, Etienne, Tremblay, Cyntia, Levert, Stéphanie, Bennett, David A., Calon, Frédéric, Leclerc, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730531/
https://www.ncbi.nlm.nih.gov/pubmed/36506473
http://dx.doi.org/10.3389/fnagi.2022.1038343

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