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The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability

The hypoxia-inducible factors (HIF) are transcription factors that activate the adaptive hypoxic response when oxygen levels are low. The HIF transcriptional program increases oxygen delivery by inducing angiogenesis and by promoting metabolic reprograming that favors glycolysis. The two major HIFs,...

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Detalles Bibliográficos
Autores principales:	Jaśkiewicz, Maciej, Moszyńska, Adrianna, Króliczewski, Jarosław, Cabaj, Aleksandra, Bartoszewska, Sylwia, Charzyńska, Agata, Gebert, Magda, Dąbrowski, Michał, Collawn, James F., Bartoszewski, Rafal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730601/ https://www.ncbi.nlm.nih.gov/pubmed/36482296 http://dx.doi.org/10.1186/s11658-022-00408-7

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