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RUNX3 mediates keloid fibroblast proliferation through deacetylation of EZH2 by SIRT1

BACKGROUND: Keloid is a benign proliferative fibrous disease featured by excessive fibroblast proliferation after skin injury. However, the mechanism of abnormal cell proliferation is still unclear. Herein, we investigated the mechanism of abnormal proliferation in keloids involving Sirtuin 1(SIRT1)...

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Detalles Bibliográficos
Autores principales:	Liu, Hanye, Yan, Guanghai, Li, Li, Wang, Dandan, Wang, Yu, Jin, Shan, Jin, Zhehu, Li, Liangchang, Zhu, Lianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730640/ https://www.ncbi.nlm.nih.gov/pubmed/36476345 http://dx.doi.org/10.1186/s12860-022-00451-4

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