MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage

BACKGROUND: The functional neurological outcome of patients with intracerebral hemorrhage (ICH) strongly relates to the degree of secondary brain injury (ICH-SBI) evolving within days after the initial bleeding. Different mechanisms including the incitement of inflammatory pathways, dysfunction of t...

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Detalles Bibliográficos
Autores principales: Akeret, Kevin, Buzzi, Raphael M., Thomson, Bart R., Schwendinger, Nina, Klohs, Jan, Schulthess-Lutz, Nadja, Baselgia, Livio, Hansen, Kerstin, Regli, Luca, Vallelian, Florence, Hugelshofer, Michael, Schaer, Dominik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730653/
https://www.ncbi.nlm.nih.gov/pubmed/36482445
http://dx.doi.org/10.1186/s12974-022-02641-5

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